How to Relieve the 8 Most Common Wegovy Side Effects Guides
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You can find a list of inactive ingredients in the package insert or ask your pharmacist. This is not all the information you need to know about Ozempic, Wegovy, Mounjaro or Zepbound for safe and effective use and does not take the place of your doctor’s directions. Tiredness (fatigue) and reactions at the injection site may also occur. Usually, your hair goes through a natural cycle of growth (anagen phase), transformation (catagen phase), and rest (telogen phase), leading to hair shedding. During the resting phase (about 3 months long), your hair stops growing and eventually sheds. If you are starting an obesity medication, beginning a daily multivitamin has little harm, he said, and can help make sure you are getting essential minerals and vitamins.
Side Effects
In Study 5, the proportions of patients who discontinued study drug were 5.8% and 11.6% for WEGOVY and placebo, respectively. In Study 6, the proportions of patients who discontinued study drug were 7.9%, 6.5%, and 3.0% for WEGOVY 1.7 mg, WEGOVY 2.4 mg, and placebo, respectively. The apparent clearance of semaglutide in patients with obesity or overweight is approximately 0.05 L/h. With an elimination half-life of approximately 1 week, semaglutide will be present in the circulation for about 5 to 7 weeks after the last dose of 2.4 mg. The steady state exposure of WEGOVY increased proportionally with doses up to 2.4 mg once weekly.
Nausea and vomiting
Although rare, it’s possible for Wegovy to cause pancreas problems to occur. And if you already have a pancreas condition, taking this medication can make your condition worse. If you have a pancreas condition, your doctor can help determine whether Wegovy may be safe for you.
Drug information
Patients with renal impairment may be at greater risk of acute kidney injury, but some of these events have been reported in patients without known underlying renal disease. A majority of the reported events occurred in patients who had experienced nausea, vomiting, or diarrhea, leading to volume depletion [see ADVERSE REACTIONS]. GLP-1 drugs, such as semaglutide, liraglutide, and tirzepatide, are type 2 diabetes medications that have become popular over the last year for weight loss. When the body experiences intense emotional or physical stress — like weight loss — it halts non-essential functions like hair growth to preserve nutrients, according to Bard.
What tips can I provide to patients to help handle nausea?
The most common adverse reactions leading to discontinuation were nausea (1.8% versus 0.2%), vomiting (1.2% versus 0%), and diarrhea (0.7% versus 0.1%) for WEGOVY and placebo, respectively. Then, one-third of the participants were switched to placebo injections for nearly a year. Eleven months after the switch, those on the placebo had regained almost 7% of their body weight, whereas participants who kept taking semaglutide continued to lose weight.
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Ozempic, Mounjaro, and others may be prescribed off-label to help with weight loss. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary.
Will hair grow back after stopping weight loss drugs?
Wegovy comes as an injection that is given once-a-week as a subcutaneous (under the skin) injection (shot) in your abdomen, thigh or upper arm. You’ll use the shot on the same day of each week, with or without a meal. Your healthcare provider will teach you how to give the shot at home for added convenience.

What is Wegovy®?
If cholelithiasis is suspected, gallbladder studies and appropriate clinical follow-up are indicated. In a cardiovascular outcomes trial, 8,803 patients were exposed to WEGOVY for a median of 37.3 months and 8,801 patients were exposed to placebo for a median of 38.6 months [see Clinical Studies]. Safety data collection was limited to serious adverse events (including death), adverse events leading to discontinuation, and adverse events of special interest. Sixteen percent (16%) of WEGOVY-treated patients and 8% of placebo-treated patients, respectively, discontinued study drug due to an adverse event.
But “by the time we’ve gotten to the GLPs, we’ve often unfortunately tried a lot of those”, Stanford says. That two-year rule “doesn’t make any clinical sense”, says clinician-researcher Alex Miras at Ulster University’s Derry–Londonderry Campus, UK, who receives research and financial support from several companies with an interest in obesity. But he acknowledges that the NICE decision came from cost-effectiveness calculations and the data the decision committee had at the time. If you take a medication to alter your biology, “the tension of the rubber band is a lot less”, he explains. “But when I take away the medication, that tension is going to come back,” says Sharma, who is based in Berlin and consults part-time for several companies that have an interest in obesity. All that means that semaglutide isn’t exactly a cure-all, in the vernacular sense.
The absolute risk was greater in patients with a history of diabetic retinopathy at baseline (8.2%[drug] vs 5.2%[placebo]) than those without (0.7%[drug] vs 0.4%[placebo]). While gallbladder disease is not as common as general stomach side effects with Wegovy, it can be much more serious. In Wegovy studies in adults, the occurrence of gallstones occurred in 1.6% of those who received Wegovy and 0.7% of those who received a placebo (an inactive shot). Gallbladder inflammation was even less common, and occurred in 0.6% of adults receiving Wegovy and 0.2% of placebo-treated patients.
If you experience nausea from taking Wegovy, talk with your doctor or pharmacist. In rare cases, nausea may occur as a symptom of another side effect. For example, you may experience nausea from kidney problems, gallbladder problems, or pancreatitis. However, children taking the drug in clinical studies were more likely to have gallbladder problems. However, if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Wegovy may not be right for you if you have certain medical conditions.
Though we often think of stressors as emotional, such as grief related to losing a loved one or divorce, Massick said that weight loss is a physical stressor to the body. For now, employers and insurers are adopting stricter tools such as prior authorization to ensure patients use the drugs appropriately, said Eileen Pincay, a national pharmacy practice leader at Segal, a benefits consultant. Drugmakers often launch drugs at higher prices when they have the exclusive right to sell medications before generic companies offer competing versions.
The dose starts low and escalates to minimize gastrointestinal side effects. “Those taking [Wegovy] should have a commitment to lifestyle changes through diet and movement and be under the supervision of their doctor and dietitian,” recommended Hill. And, as is usually the case, Wegovy is meant to be one tool of many in achieving and maintaining a healthy weight. It’s also meant for long-term use, so an expectation of long-term insurance coverage and a discussion with a doctor should both be factors in deciding whether this medication is right for you.
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